Article
Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation.
Developmental biology - 1 Sept 2013
Jin Jiu-Zhen, Ding Jixiang
Abstract excerpt
During mouse gastrulation, cells in the primitive streak undergo epithelial-mesenchymal transformation and the resulting mesenchymal cells migrate out laterally to form mesoderm and definitive endoderm across the entire embryonic cylinder. The mechanisms underlying mesoderm and endoderm specification, migration, and allocation are poorly understood. In this study, we focused on the function of mouse Cripto, a...
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