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Article

Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo.

Development (Cambridge, England) - 1 Sept 2008

García-García María J, Shibata Maho, Anderson Kathryn V

Abstract excerpt

In Xenopus and zebrafish embryos, elongation of the anterior-posterior body axis depends on convergent extension, a process that involves polarized cell movements and is regulated by non-canonical Wnt signaling. The mechanisms that control axis elongation of the mouse embryo are much less well understood. Here, we characterize the ENU-induced mouse mutation chato, which causes arrest at midgestation and defects...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18701545
DOI: 10.1242/dev.022897
PMCID: PMC2583081

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo.PMID 18701545Read ↗

The mouse KRAB zinc-finger protein CHATO is required in embryonic-derived tissues to control yolk sac and placenta morphogenesis.Semantic proximity Read ↗

The zinc-finger protein CNBP is required for forebrain formation in the mouse.Semantic proximity Read ↗

Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast.Semantic proximity Read ↗

Regulation of axial elongation by Cdx.Semantic proximity Read ↗

cato encodes a basic helix-loop-helix transcription factor implicated in the correct differentiation of Drosophila sense organs.Semantic proximity Read ↗

Wnt8a and Wnt3a cooperate in the axial stem cell niche to promote mammalian body axis extension.Semantic proximity Read ↗

Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo.Semantic proximity Read ↗

Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve gangliaSemantic proximity Read ↗

Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration.Semantic proximity Read ↗

A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain.Semantic proximity Read ↗

oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1.Semantic proximity Read ↗

Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation.Semantic proximity Read ↗

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