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Visceral endoderm and the primitive streak interact to build the fetal-placental interface of the mouse gastrula

5 Sept 2017

Abstract excerpt

Hypoblast/visceral endoderm assists in amniote nutrition, axial positioning and formation of the gut. Here, we provide evidence, currently limited to humans and non-human primates, that hypoblast is a purveyor of extraembryonic mesoderm in the mouse gastrula. Fate mapping a unique segment of axial extraembryonic visceral endoderm associated with the allantoic component of the primitive streak, and referred to as...

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Identifiers

PMID: 28882402
DOI: 10.1016/j.ydbio.2017.08.026

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