Article
Mitogen-activated protein kinases MpkA and MpkB independently affect micafungin sensitivity in Aspergillus nidulans.
Bioscience, biotechnology, and biochemistry - 1 Jan 2015
Yoshimi Akira, Fujioka Tomonori, Mizutani Osamu, Marui Junichiro, Hagiwara Daisuke, Abe Keietsu
Abstract excerpt
The transcriptional regulation of the MAPK mpkA and cell wall-related genes in Aspergillus nidulans differs from that of their counterparts in Saccharomyces cerevisiae. The A. nidulans MAPK MpkB is putatively orthologous to the yeast MAPKs Kss1p and Fus3p. To investigate MpkB and its contribution to cell wall integrity in A. nidulans, we constructed mpkB-disruptant (mpkB∆) strains. We previously showed that mpkA∆...
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