Article
Transcription and diversity of immunoglobulin lambda chain variable genes in the rat.
Immunogenetics - 1 Jan 1992
Aguilar B A, Gutman G A
Abstract excerpt
In order to determine the extent of the repertoire of the immunoglobulin light chain V-region locus (Igl-V) in the laboratory rat (Rattus norvegicus), we constructed a specifically primed cDNA library from lipopolysaccharide-stimulated DA strain rat spleens. The library was screened with a rat Ig...
Topics
- Amino Acid Sequence
- Animals
- Autoradiography
- Base Sequence
- Blotting, Southern
- DNA
- Genetic Variation
- Immunoglobulin Variable Region
- Immunoglobulin lambda-Chains
- Molecular Sequence Data
- Phylogeny
- Rats
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid
- Transcription, Genetic