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Article

Transcription and diversity of immunoglobulin lambda chain variable genes in the rat.

Immunogenetics - 1 Jan 1992

Aguilar B A, Gutman G A

Abstract excerpt

In order to determine the extent of the repertoire of the immunoglobulin light chain V-region locus (Igl-V) in the laboratory rat (Rattus norvegicus), we constructed a specifically primed cDNA library from lipopolysaccharide-stimulated DA strain rat spleens. The library was screened with a rat Igl-C2-specific probe, and 33 clones containing identifiable V regions were sequenced, of which 19 sequences are...

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PMID: 1428010
DOI: 10.1007/BF00223543

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