Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of signaling molecule genes resembling the cytoplasmic domain of Igbeta in autoimmune-prone mice.

International immunology - 1 Jun 1998

Maeda T, Webb D R, Chen J, Kobata T, Hirose S, Shirai T, Takabayashi K, Nishioka K, Sumida T

Abstract excerpt

The P8.6 gene is encoded upstream of the mouse TCR Valpha1 gene in the anti-sense strand and its gene product contains the proline-rich region and tyrosine-isoleucine (Y-I) motif, which are consensus sequences for the SH2 and SH3 binding motifs respectively. It was found that this protein is highly homologous to Igbeta. We also found that the P8.6 protein associates with a 170 kDa phosphorylated protein in vivo....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Blotting, Southern

Share to Carrier Proteins

Share to Cloning, Molecular

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 9678763
DOI: 10.1093/intimm/10.6.815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of signaling molecule genes resembling the cytoplasmic domain of Igbeta in autoimmune-prone mice.PMID 9678763Read ↗

Acquiring signalling specificity from the cytokine receptor gp130.Semantic proximity Read ↗

Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice.Semantic proximity Read ↗

Functional dissection of the cytoplasmic subregions of the interleukin-5 receptor alpha chain in growth and immunoglobulin G1 switch recombination of B cells.Semantic proximity Read ↗

Large deletion on the Y-chromosome long arm (Yq) of C57BL/6JBomTac inbred mice.Semantic proximity Read ↗

Generation of a Mig-6 conditional null allele.Semantic proximity Read ↗

A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse.Semantic proximity Read ↗

Transcriptional Repression of Stat6-Dependent Interleukin-4-Induced Genes by BCL-6: Specific Regulation of Iɛ Transcription and Immunoglobulin E SwitchingSemantic proximity Read ↗

Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene.Semantic proximity Read ↗

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.Semantic proximity Read ↗

IL-1 beta-deficient mice are resistant to induction of experimental SLE.Semantic proximity Read ↗

Alternative Intronic Polyadenylation Generates the Interleukin-6 Trans-signaling Inhibitor sgp130-E10Semantic proximity Read ↗

Mapping of the BALB/c Ly49 cluster defines a minimal natural killer cell receptor gene repertoire.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.