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Article

Hypospadias and genes related to genital tubercle and early urethral development.

The Journal of urology - 1 Nov 2013

Carmichael Suzan L, Ma Chen, Choudhry Shweta, Lammer Edward J, Witte John S, Shaw Gary M

Abstract excerpt

PURPOSE: We determined whether variants in genes associated with genital tubercle (the anlage for the penis) and early urethral development were associated with hypospadias in humans. MATERIALS AND METHODS: We examined 293 relatively common tag single nucleotide polymorphisms in BMP4, BMP7, FGF8, FGF10, FGFR2, HOXA13, HOXD13, HOXA4, HOXB6, SRY, WT1, WTAP, SHH, GLI1, GLI2 and GLI3. The analysis included 624 cases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23727413
DOI: 10.1016/j.juro.2013.05.061
PMCID: PMC4103581

Genes

BMP7
FGF10
GLI1
GLI2
GLI3
SHH
BMP4
FGF8
FGFR2
HOXA13
HOXA4
HOXB6
HOXD13
SRY
WTAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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