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Genetic Susceptibility and Pathogenesis of Hypospadias.

Biochemical genetics - 1 Jun 2026

Ajayi Ayodeji Folorunsho, Oyowvi Mega Obukohwo, Akanbi Grace Bosede, Ajayi Lydia Oluwatoyin, Ayomide Jonathan Jegede

Abstract excerpt

This study examines the genetic susceptibility and pathogenesis of hypospadias. Hypospadias is a birth defect of the urethra where the urinary opening is on the underside of the penis rather than at the tip. This study aims to identify the genetic basis of this defect and, by extension, improve our understanding of the biological pathways involved in its pathogenesis. Novel genetic loci and variants associated...

Topics

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Epigenesis, Genetic
Genetic Predisposition to Disease
Genome-Wide Association Study
Hypospadias

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40663283
DOI: 10.1007/s10528-025-11199-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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