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The genetic factors contributing to hypospadias and their clinical utility in its diagnosis

21 Sept 2018

Abstract excerpt

Hypospadias is among the most common congenital malformations in male neonates. It results from abnormal penile and urethral development, but is a multifactorial disorder that is highly heterogeneous, with several genetic and environmental determinants. Monogenic and chromosomal abnormalities are present in approximately 30% of cases, although the genetic factors contributing to hypospadias remain unknown in 70%...

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PMID: 30238986
DOI: 10.1002/jcp.27350

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