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Article

The Genomic Architecture of Bladder Exstrophy Epispadias Complex.

Genes - 28 Jul 2021

Beaman Glenda M, Cervellione Raimondo M, Keene David, Reutter Heiko, Newman William G

Abstract excerpt

The bladder exstrophy-epispadias complex (BEEC) is an abdominal midline malformation comprising a spectrum of congenital genitourinary abnormalities of the abdominal wall, pelvis, urinary tract, genitalia, anus, and spine. The vast majority of BEEC cases are classified as non-syndromic and the etiology of this malformation is still unknown. This review presents the current knowledge on this multifactorial...

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PMID: 34440323
DOI: 10.3390/genes12081149
PMCID: PMC8391660

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