Article
Mismatch repair proteins in recurrent prostate cancer.
Advances in clinical chemistry - 1 Jan 2013
Jarzen John, Diamanduros Andrew, Scarpinato Karin D
Abstract excerpt
Normal cell function requires strict control over the repair of DNA damage, which prevents excessive mutagenesis. An enhanced accumulation of mutations results in the multistep process generally known as carcinogenesis. Defects in repair pathways fuel such mutagenesis by allowing reiterative cycl...
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