Contribution of Murine Double Minute 2 Genotypes to Colorectal Cancer Risk in Taiwan.

doi:10.21873/cgp.20099

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Contribution of Murine Double Minute 2 Genotypes to Colorectal Cancer Risk in Taiwan.

Cancer genomics & proteomics - 1 Jan 2000

Yueh Te-Cheng, Hung Yi-Wen, Shih Tzu-Ching, Wu Cheng-Nan, Wang Shou-Cheng, Lai Yi-Liang, Hsu Shih-Wei, Wu Ming-Hsien, Fu Chun-Kai, Wang Yun-Chi, Ke Tao-Wei, Chang Wen-Shin, Tsai Chia-Wen, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: The genomic role of human mouse double minute 2 (MDM2) in colorectal cancer (CRC) is unclear, therefore, our study aimed to evaluate the contribution of MDM2 genotype to the risk of CRC in Taiwan. MATERIALS AND METHODS: In this case-control study, MDM2 SNP309 T to G (rs2279744) genotypes were determined and their association with CRC risk were investigated among 362 patients with CRC and 362 age-...

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PMID: 30194081
DOI: 10.21873/cgp.20099
PMCID: PMC6199579

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