Article
T-cell receptor beta-chain DNA polymorphism frequencies in healthy HLA-DR homozygotes.
Tissue antigens - 1 Apr 1990
Charmley P, Concannon P, Gatti R A
Abstract excerpt
In view of numerous recent reports of T-cell receptor (TCR) beta-chain/disease associations with HLA-associated diseases, we tested the possibilities that associations might exist directly between these two gene complexes at the level of the germline DNA. We determined frequencies of five TCR-beta DNA polymorphisms in 33 HLA-DR2/2 homozygotes, 29 HLA-DR3/3 homozygotes and 42 HLA-DR4/4 homozygotes. The control...
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