Article
Distribution of polymorphic HLA-DR and -DQ alleles as determined by restriction fragment length polymorphism analysis in an Austrian population.
Vox sanguinis - 1 Jan 1992
Fischer G F, Faé I, Pickl W F
Abstract excerpt
The restriction fragment length polymorphism (RFLP) of HLA-DR beta, -DQ alpha and -DQ beta genes was analyzed in 637 unrelated individuals from the Austrian population. The restriction enzyme was Taq I, and three exon-specific probes were applied. The gene frequencies, the Hardy-Weinberg equilibrium in DR beta and DQ loci, linkage disequilibria between the loci and haplotype frequencies are calculated. Rare...
Topics
- Alleles
- Austria
- Blood Donors
- Female
- Gene Frequency
- Genes, MHC Class II
- HLA-DQ Antigens
- HLA-DR Antigens
- Haplotypes
- Humans
- Linkage Disequilibrium
- Male
