DNA-RFLP analysis and genotyping of HLA-DR alleles in the south of Spain.

Article

DNA-RFLP analysis and genotyping of HLA-DR alleles in the south of Spain.

Experimental and clinical immunogenetics - 1 Jan 1991

Martín J, Almeida D, Mialdea M J, Rodriguez M, Mataran L, Garrido F

Abstract excerpt

42 healthy individuals previously HLA-DR typed by serology, were HLA class II typed using RFLPs. The pattern of hybridization revealed allele specific DNA fragments for some DR specificities. Three fragments highly associated with HLA-DR antigens: a 7 kb RFLP with DR1; a 10 kb RFLP with DR-3/DR-5...

Topics

Alleles
DNA
Genotype
HLA-DR Antigens
Histocompatibility Testing
Humans
Polymorphism, Restriction Fragment Length
Spain

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