Article
Host APOL1 genotype is independently associated with proteinuria in HIV infection.
Kidney international - 1 Oct 2013
Estrella Michelle M, Wyatt Christina M, Pearce C Leigh, Li Man, Shlipak Michael G, Aouizerat Bradley E, Gustafson Deborah, Cohen Mardge H, Gange Stephen J, Kao W H Linda, Parekh Rulan S
Abstract excerpt
Proteinuria is associated with adverse clinical outcomes in HIV infection. Here we evaluated whether APOL1 risk alleles, previously associated with advanced kidney disease, are independently associated with proteinuria in HIV infection in a cross-sectional study of HIV-infected women in the Women's Interagency HIV Study. We estimated the percent difference in urine protein excretion and odds of proteinuria...
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