Article
APOL1 Risk Variants Are Strongly Associated with HIV-Associated Nephropathy in Black South Africans.
Journal of the American Society of Nephrology : JASN - 1 Nov 2015
Kasembeli Alex N, Duarte Raquel, Ramsay Michèle, Mosiane Pulane, Dickens Caroline, Dix-Peek Thérèse, Limou Sophie, Sezgin Efe, Nelson George W, Fogo Agnes B, Goetsch Stewart, Kopp Jeffrey B, Winkler Cheryl A, Naicker Saraladevi
Abstract excerpt
APOL1 variants are associated with HIV-associated nephropathy and FSGS in African Americans. The prevalence of these variants in African populations with CKD in HIV-1 infection has not been investigated. We determined the role of APOL1 variants in 120 patients with HIV-associated nephropathy and CKD and 108 controls from a South-African black population. Patients with CKD were selected on the basis of histology....
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