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Article

The effect of CHEK2 variant I157T on cancer susceptibility: evidence from a meta-analysis.

DNA and cell biology - 1 Jun 2013

Han Fei-fei, Guo Chang-long, Liu Li-hong

Abstract excerpt

Cell cycle checkpoint kinase 2 (CHEK2) is a checkpoint kinase that plays an important role in the DNA damage signaling network. Numerous epidemiological studies have evaluated the association between the CHEK2 I157T variant and cancer susceptibility. However, the results of these studies on the association remain conflicting. The main purpose of this study was to integrate previous results and explore whether the...

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Identifiers

PMID: 23713947
DOI: 10.1089/dna.2013.1970

Genes

CHEK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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