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Article

The associations of sequence variants in DNA-repair and cell-cycle genes with cancer risk: genotype-phenotype correlations.

Biochemical Society transactions - 1 Jun 2009

Hall Janet, Marcel Virginie, Bolin Celeste, Fernet Marie, Tartier Laurence, Vaslin Laurence, Hainaut Pierre

Abstract excerpt

DNA-repair systems maintain the integrity of the human genome, and cell-cycle checkpoints are a critical component of the cellular response to DNA damage. Thus the presence of sequence variants in genes involved in these pathways that modulate their activity might have an impact on cancer risk. Many molecular epidemiological studies have investigated the association between sequence variants, particularly SNPs...

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Source

Identifiers

PMID: 19442246
DOI: 10.1042/BST0370527

Genes

CHEK2
ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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