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Article

Prospects for identifying functional variation across the genome.

Proceedings of the National Academy of Sciences of the United States of America - 3 May 2005

Macdonald Stuart J, Long Anthony D

Abstract excerpt

The genetic factors contributing to complex trait variation may reside in regulatory, rather than protein-coding portions of the genome. Within noncoding regions, SNPs in regulatory elements are more likely to contribute to phenotypic variation than those in nonregulatory regions. Thus, it is important to be able to identify and annotate noncoding regulatory elements. DNA conservation among diverged species...

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PMID: 15851675
DOI: 10.1073/pnas.0501990102
PMCID: PMC1131871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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