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Article

Natural variation of gene models in Drosophila melanogaster.

BMC genomics - 17 Mar 2015

Kurmangaliyev Yerbol Z, Favorov Alexander V, Osman Noha M, Lehmann Kjong-Van, Campo Daniel, Salomon Matthew P, Tower John, Gelfand Mikhail S, Nuzhdin Sergey V

Abstract excerpt

BACKGROUND: Variation within splicing regulatory sequences often leads to differences in gene models among individuals within a species. Two alleles of the same gene may express transcripts with different exon/intron structures and consequently produce functionally different proteins. Matching genomic and transcriptomic data allows us to identify putative regulatory variants associated with changes in splicing...

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Identifiers

PMID: 25888292
DOI: 10.1186/s12864-015-1415-6
PMCID: PMC4373058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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