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Article

Role of chemical structures and the 1331T>C bile salt export pump polymorphism in idiosyncratic drug-induced liver injury.

Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2013

Ulzurrun Eugenia, Stephens Camilla, Crespo Esperanza, Ruiz-Cabello Francisco, Ruiz-Nuñez Julia, Saenz-López Pablo, Moreno-Herrera Inmaculada, Robles-Díaz Mercedes, Hallal Hacibe, Moreno-Planas José M, Cabello Maria R, Lucena M Isabel, Andrade Raúl J

Abstract excerpt

BACKGROUND & AIMS: Several pharmaceutical compounds have been shown to exert inhibitory effects on the bile salt export pump (BSEP) encoded by the ABCB11 gene. We analysed the combined effect on drug-induced liver injury (DILI) development of the ABCB11 1331T>C polymorphism and the presence of sp...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 11
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23701583
DOI: 10.1111/liv.12193

Genes

ABCB11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23701583-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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