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Article

Pharmacokinetic interactions and safety evaluations of coadministered tafenoquine and chloroquine in healthy subjects.

British journal of clinical pharmacology - 1 Dec 2013

Miller Ann K, Harrell Emma, Ye Li, Baptiste-Brown Sharon, Kleim Jőrg-Peter, Ohrt Colin, Duparc Stephan, Möhrle Jörg J, Webster Alison, Stinnett Sandra, Hughes Arlene, Griffith Sandy, Beelen Andrew P

Abstract excerpt

AIMS: The long-acting 8-aminoquinoline tafenoquine (TQ) coadministered with chloroquine (CQ) may radically cure Plasmodium vivax malaria. Coadministration therapy was evaluated for a pharmacokinetic interaction and for pharmacodynamic, safety and tolerability characteristics. METHODS: Healthy subjects, 18-55 years old, without documented glucose-6-phosphate dehydrogenase deficiency, received CQ alone (days 1-2,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23701202
DOI: 10.1111/bcp.12160
PMCID: PMC3845309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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