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Article

Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum.

Malaria journal - 25 May 2010

Parquet Véronique, Henry Maud, Wurtz Nathalie, Dormoi Jerome, Briolant Sébastien, Gil Marine, Baret Eric, Amalvict Rémy, Rogier Christophe, Pradines Bruno

Abstract excerpt

BACKGROUND: Quinine (QN) remains the first line anti-malarial drug for the treatment of complicated malaria in Europe and Africa. The emergence of QN resistance has been documented. QN resistance is not yet a significant problem, but there is an urgent need to discover partners for use in combination with QN. The aim of the study was to assess the in vitro potentiating effects of atorvastatin (AVA), a...

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Identifiers

PMID: 20497586
DOI: 10.1186/1475-2875-9-139
PMCID: PMC2882376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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