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Article

ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions.

Cancer research - 15 Jul 2013

Singh Thiyam Ramsing, Ali Abdullah Mahmood, Paramasivam Manikandan, Pradhan Arun, Wahengbam Kebola, Seidman Michael M, Meetei Amom Ruhikanta

Abstract excerpt

Fanconi anemia (FA) is a genome instability syndrome that has been associated with both cancer predisposition and bone marrow failure. FA proteins are involved in cellular response to replication stress in which they coordinate DNA repair with DNA replication and cell-cycle progression. One regulator of the replication stress response is the ATP-dependent DNA translocase FANCM, which we have shown to be...

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Identifiers

PMID: 23698467
DOI: 10.1158/0008-5472.CAN-12-3976
PMCID: PMC3732194

Genes

FANCM
ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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