Article

Morphological predictors for microsatellite instability in urothelial carcinoma

2021-06-24

Abstract excerpt

<title>Abstract</title> <p>IntroductionMicrosatellite instability occurs due to a series of mutations in the DNA pairing error repair (Mismatch repair; MMR) genes, which can affect germ cells as occurs in Lynch syndrome, whose patients are at high risk of developing multiple cancers. The loss of MMR protein is commonly determined by immunohistochemical studies. Although the relation between microsatellite instabi...

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Literature Corpus work: 834dc0ea-55e7-5ea2-b54e-735bf3f7aee6
DOI: 10.21203/rs.3.rs-646067/v1

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