Article
Pesticide exposure and genetic variation in xenobiotic-metabolizing enzymes interact to induce biochemical liver damage.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Nov 2013
Hernández Antonio F, Gil Fernando, Lacasaña Marina, Rodríguez-Barranco Miguel, Tsatsakis Aristidis M, Requena Mar, Parrón Tesifón, Alarcón Raquel
Abstract excerpt
Metabolic activation of pesticides in the liver may result in highly reactive intermediates capable of impairing various cellular functions. Nevertheless, the knowledge about the effect of pesticide exposure on liver function is still limited. This study assessed whether exposure to pesticides elicits early biochemical changes in biomarkers of liver function and looked for potential gene-environmental...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.