Article
Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.
Environmental health perspectives - 1 Oct 2010
Howard Timothy D, Hsu Fang-Chi, Grzywacz Joseph G, Chen Haiying, Quandt Sara A, Vallejos Quirina M, Whalley Lara E, Cui Wei, Padilla Stephanie, Arcury Thomas A
Abstract excerpt
BACKGROUND: Organophosphate pesticides act as cholinesterase inhibitors. For those with agricultural exposure to these chemicals, risk of potential exposure-related health effects may be modified by genetic variability in cholinesterase metabolism. Cholinesterase activity is a useful, indirect measurement of pesticide exposure, especially in high-risk individuals such as farmworkers. To understand fully the links...
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