Article
SATB1 collaborates with loss of p16 in cellular transformation.
Oncogene - 28 Nov 2013
Agrelo R, Kishimoto H, Novatchkova M, Peraza V, Paolino M, Souabni A, Wutz A
Abstract excerpt
Tumor progression is associated with invasiveness and metastatic potential. The special AT-rich binding protein 1 (SATB1) has been identified as a key factor in the progression of breast cancer cells to a malignant phenotype and is associated with progression of human tumors. In normal development, SATB1 coordinates gene expression of progenitor cells by functioning as a genome organizer. In contrast to...
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