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Article

Is SATB1 a master regulator in breast cancer growth and metastasis?

Women's health (London, England) - 1 Jul 2008

Zheng Jie

Abstract excerpt

Evaluation of: Han HJ, Russo J, Kohwi Y et al.: SATB1 reprogrammes gene expression to promote breast tumor growth and metastasis. Nature 452(7184), 187-193 (2008). Metastasis is the most common cause of death in cancer patients. However, the genetic mechanisms involved in the master control genes of metastasis remain unclear. In this study, the authors found that special AT-rich sequence-binding protein 1 (SATB1)...

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Share to Breast Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Matrix Attachment Region Binding Proteins

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Source

Identifiers

PMID: 19072498
DOI: 10.2217/17455057.4.4.329

Genes

SATB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Is SATB1 a master regulator in breast cancer growth and metastasis?PMID 19072498Read ↗

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Genome Organizer SATB1 selectively activates a defined subset of EMT genes driving metastatic breast cancerSemantic proximity Read ↗

ATM suppresses SATB1-induced malignant progression in breast epithelial cells.Semantic proximity Read ↗

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SATB1 expression is associated with biologic behavior in colorectal carcinoma in vitro and in vivo.Semantic proximity Read ↗

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Tetramerization of SATB1 is essential for regulating of gene expression.Semantic proximity Read ↗

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