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Article

SATB2 is a novel biomarker and therapeutic target for cancer

4 Sept 2020

Abstract excerpt

Several studies have confirmed the involvement of cancer stem cells (CSC) in tumour progression, metastasis, drug resistance and cancer relapse. SATB2 (special AT-rich binding protein-2) acts as a transcriptional co-factor and modulates chromatin architecture to regulate gene expression. The purpose of this review was to discuss the pathophysiological roles of SATB2 and assess whether it could be used as a...

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PMID: 32885593
DOI: 10.1111/jcmm.15755

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