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Article

Special AT-rich sequence binding protein 1 regulates the multidrug resistance and invasion of human gastric cancer cells

17 Apr 2012

Abstract excerpt

Special AT-rich sequence binding protein 1 (SATB1) is a nuclear factor that functions as a global chromatin organizer to regulate gene expression. Recent studies have suggested an oncogenic role of SATB1 in breast cancer. However, the role of SATB1 in gastric cancer, especially in regulating the malignant phenotypes, including multidrug resistance (MDR) and metastasis, remains poorly understood. In this study,...

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PMID: 22807980
DOI: 10.3892/ol.2012.681

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