Article
The 46359CT polymorphism of DNMT3B is associated with the risk of cervical cancer.
Molecular biology reports - 1 Jul 2013
Hernández-Sotelo Daniel, García-Aguilar Rubén, Castro-Coronel Yaneth, Magaña Jonathan J, Leyva-Vazquez Marco Antonio, Alarcón-Romero Luz del Carmen, López-Bayghen Esther, Illades-Aguiar Berenice
Abstract excerpt
Abnormal methylation is related to cancer development. Since DNMT3B is an enzyme that modulates genomic methylation, we hypothesized that genetic variants of the promoter DNMT3B may be associated with an increased risk of developing cervical cancer. Our aim was to investigate the association betw...
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