Article
Promoter polymorphisms of DNMT3B and the risk of head and neck squamous cell carcinoma in Taiwan: a case-control study.
Oral oncology - 1 Apr 2007
Chang Kai-Ping, Hao Sheng-Po, Liu Chun-Ting, Cheng Ming-Huei, Chang Yu-Liang, Lee Yun-Shien, Wang Tzu-Hao, Tsai Chi-Neu
Abstract excerpt
Three single nucleotide polymorphisms (SNPs) of the DNMT3B promoter region, C46359T (-149C>T), -283T>C, and -579G>T might be a cancer susceptible factor for several cancers. In this study, we genotyped 226 head-and-neck squamous-cell carcinoma (HNSCC) patients and 249 controls to examine the association between three SNPs of the DNMT3B promoter and the associated risk of the development and/or metastasizing...
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