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Article

Two-stage case-control study of DNMT-1 and DNMT-3B gene variants and breast cancer risk.

Breast cancer research and treatment - 1 Jun 2010

Ye Chuanzhong, Beeghly-Fadiel Alicia, Lu Wei, Long Jirong, Shu Xiao Ou, Gao Yu-Tang, Zheng Wei, Cai Qiuyin

Abstract excerpt

Aberrant DNA methylation of CpG islands is a common epigenetic alteration found in cancers. DNA methylation is typically mediated by DNA methyltransferases (DNMTs). Only two studies have evaluated DNMT-1 and/or DNMT-3B gene polymorphisms in relation to breast cancer risk, and results have been in...

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Identifiers

PMID: 19798569
DOI: 10.1007/s10549-009-0569-9
PMCID: PMC3493111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19798569-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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