Article
DNMT3B 579 G>T promoter polymorphism and risk of esophagus carcinoma in Chinese.
World journal of gastroenterology - 14 Apr 2008
Fan Hong, Liu Dong-Sheng, Zhang Shu-Hong, Hu Jia-Bo, Zhang Feng, Zhao Zhu-Jiang
Abstract excerpt
AIM: To investigate the relationship between 579 G>T polymorphisms in the DNMT3B gene, which is involved in de novo methylation and associated with the risk of esophagus cancer (EC) in Chinese. METHODS: DNMT3B 579 G>T genotypes were determined by PCR-RFLP in 194 EC patients and 210 healthy controls matched for age and sex, who did not receive radiotherapy or chemotherapy for newly diagnosed and...
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