Article
Genetic redundancy strengthens the circadian clock leading to a narrow entrainment range.
Journal of the Royal Society, Interface - 6 Jul 2013
Erzberger A, Hampp G, Granada A E, Albrecht U, Herzel H
Abstract excerpt
Circadian clocks are internal timekeepers present in almost all organisms. Driven by a genetic network of highly conserved structure, they generate self-sustained oscillations that entrain to periodic external signals such as the 24 h light-dark cycle. Vertebrates possess multiple, functionally overlapping homologues of the core clock genes. Furthermore, vertebrate clocks entrain to a range of periods three times...
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