Article
Loss- and gain-of-function analyses of vacuolar protein sorting 2 in Notch signaling of Drosophila melanogaster.
Genes & genetic systems - 1 Jan 2013
Aoyama Naoki, Yamakawa Tomoko, Sasamura Takeshi, Yoshida Yuka, Ohori Maki, Okubo Hiroyuki, Iida Eriko, Sasaki Nobuo, Ueda Ryu, Matsuno Kenji
Abstract excerpt
Notch signaling is an evolutionarily conserved mechanism that controls many cell-fate specifications through local cell-cell interactions. The core mechanisms of Notch activation and its subsequent intracellular signaling are well understood. Various cellular functions are required for the activation and regulation of Notch signaling. Among them, the endocytosis of Notch and its ligands is important for the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
