Article
vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis.
Development (Cambridge, England) - 1 May 2006
Herz Hans-Martin, Chen Zhihong, Scherr Heather, Lackey Melinda, Bolduc Clare, Bergmann Andreas
Abstract excerpt
Appropriate cell-cell signaling is crucial for proper tissue homeostasis. Protein sorting of cell surface receptors at the early endosome is important for both the delivery of the signal and the inactivation of the receptor, and its alteration can cause malignancies including cancer. In a genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
