Article
Targeted ANP32E mutant mice do not demonstrate obvious movement defects.
PloS one - 1 Jan 2013
Wong Peiyan, Leo Vonny I, Low Meijun, Mak Tak W, Zhang Xiaodong, Reilly Patrick T
Abstract excerpt
BACKGROUND: The ANP32 family of proteins have been implicated in neuronal function through biochemical and cellular biology studies in neurons, as well as by recent behavioural studies of a gene-trapped loss-of-function mutation of Anp32e in mice, particularly with respect to fine motor function. A second targeted allele of the Anp32e, however, did not appear to demonstrate neurological phenotypes....
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