Article
Towards new models of disease and physiology in the neurosciences: the role of induced and naturally occurring mutations.
Human molecular genetics - 12 Apr 2000
Hunter A J, Nolan P M, Brown S D
Abstract excerpt
There is a dearth of good mouse models for central nervous system (CNS) disorders. However, the development of gene-targeted technology and the recognition of the importance of the mouse as a model organism have led to the development of a range of behavioural tests for mice. Spontaneous mutations in mice have already provided important information about the role of novel gene products in disorders such as...
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