Article
Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 2011
Reilly Patrick T, Afzal Samia, Gorrini Chiara, Lui Koren, Bukhman Yury V, Wakeham Andrew, Haight Jillian, Ling Teo Wei, Cheung Carol C, Elia Andrew J, Turner Patricia V, Mak Tak Wah
Abstract excerpt
The highly conserved ANP32 proteins are proposed to function in a broad array of physiological activities through molecular mechanisms as diverse as phosphatase inhibition, chromatin regulation, caspase activation, and intracellular transport. On the basis of previous analyses of mice bearing targeted mutations of Anp32a or Anp32e, there has been speculation that all ANP32 proteins play redundant roles and are...
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