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Article

Ablation of retinal ciliopathy protein RPGR results in altered photoreceptor ciliary composition.

Scientific reports - 11 Jun 2015

Rao Kollu N, Li Linjing, Anand Manisha, Khanna Hemant

Abstract excerpt

Cilia regulate several developmental and homeostatic pathways that are critical to survival. Sensory cilia of photoreceptors regulate phototransduction cascade for visual processing. Mutations in the ciliary protein RPGR (retinitis pigmentosa GTPase regulator) are a prominent cause of severe blindness disorders due to degeneration of mature photoreceptors. However, precise function of RPGR is still unclear. Here...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26068394
DOI: 10.1038/srep11137
PMCID: PMC4463945

Genes

RPGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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