Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors.

doi:10.1080/15384101.2014.998085

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Article

Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Bendris Nawal, Lemmers Bénédicte, Blanchard Jean Marie

Abstract excerpt

While targeting experiments carried out on the genes encoding many cell cycle regulators have challenged our views of cell cycle control, they also suggest that redundancy might not be the only explanation for the observed perplexing phenotypes. Indeed, several observations hint at functions of cyclins and CDK inhibitors that cannot be accounted for by their sole role as kinase regulators. They are found involved...

Topics

Animals
Cell Cycle
Cell Nucleus
Cyclin D1
Cyclin E
Cyclin-Dependent Kinases
Cyclins
Cytoplasm
Cytoskeleton
DNA Damage
DNA Repair
Epithelial-Mesenchymal Transition
Female
Humans
Interphase
Male
Mice
Mitosis

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Open in PubMed Open full text

Identifiers

PMID: 25789852
DOI: 10.1080/15384101.2014.998085
PMCID: PMC4614797

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