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Secretome Analysis Defines the Major Role of SecDF in Staphylococcus aureus Virulence

3 May 2013

Abstract excerpt

The Sec pathway plays a prominent role in protein export and membrane insertion, including the secretion of major bacterial virulence determinants. The accessory Sec constituent SecDF has been proposed to contribute to protein export. Deletion of Staphylococcus aureus secDF has previously been shown to reduce resistance, to alter cell separation, and to change the expression of certain virulence factors. To...

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PMID: 23658837
DOI: 10.1371/journal.pone.0063513

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