Article
Exoproteome Profiling Reveals the Involvement of the Foldase PrsA in the Cell Surface Properties and Pathogenesis of Staphylococcus aureus.
Proteomics - 1 Mar 2018
Lin Mei-Hui, Li Chi-Chun, Shu Jwu-Ching, Chu Hao-Wei, Liu Chao-Chin, Wu Chih-Ching
Abstract excerpt
Staphylococcus aureus is a bacterial pathogen that produces and exports many virulence factors that cause diseases in humans. PrsA, a membrane-bound foldase, is expressed ubiquitously in Gram-positive bacteria and required for the folding of exported proteins into a stable and active structure. To understand the involvement of PrsA in posttranslocational protein folding in S. aureus, a PrsA-deficient mutant of S....
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