Article
SecDF as part of the Sec-translocase facilitates efficient secretion of Bacillus cereus toxins and cell wall-associated proteins.
PloS one - 1 Jan 2014
Vörös Aniko, Simm Roger, Slamti Leyla, McKay Matthew J, Hegna Ida K, Nielsen-LeRoux Christina, Hassan Karl A, Paulsen Ian T, Lereclus Didier, Økstad Ole Andreas, Molloy Mark P, Kolstø Anne-Brit
Abstract excerpt
The aim of this study was to explore the role of SecDF in protein secretion in Bacillus cereus ATCC 14579 by in-depth characterization of a markerless secDF knock out mutant. Deletion of secDF resulted in pleiotropic effects characterized by a moderately slower growth rate, aberrant cell morphology, enhanced susceptibility to xenobiotics, reduced virulence and motility. Most toxins, including food...
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