Article
Isolation of a Membrane Protein Complex for Type VII Secretion in Staphylococcus aureus.
Journal of bacteriology - 1 Dec 2017
Aly Khaled A, Anderson Mark, Ohr Ryan Jay, Missiakas Dominique
Abstract excerpt
The ESAT6-like secretion system (ESS) of Staphylococcus aureus promotes effector protein transport across the bacterial envelope. Genes in the ESS cluster are required for S. aureus establishment of persistent abscess lesions and the modulation of immune responses during bloodstream infections. However, the biochemical functions of most of the ESS gene products, specifically the identity of secretion machine...
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