Article

The Drosophila Amyloid Precursor Protein homologue mediates neuronal survival and neuro-glial interactions

2020-03-09

Abstract excerpt

The amyloid precursor protein (APP) is a structurally and functionally conserved transmembrane protein whose physiological role in adult brain function and health is still unclear. Because mutations in APP cause familial Alzheimer’s disease, most research focuses on this aspect of APP biology. We investigated the physiological function of APP in the adult brain using the fruit fly Drosophila melanogaster , which...

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Literature Corpus work: 741052f1-cc16-59ee-a202-80189be52d8a
DOI: 10.1101/2020.03.09.983353

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