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Article

Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.

Molecular biology of the cell - 1 Jan 2008

Shrivastava-Ranjan Punya, Faundez Victor, Fang Guofu, Rees Howard, Lah James J, Levey Allan I, Kahn Richard A

Abstract excerpt

Beta-amyloid peptides (Abeta) are the major component of plaques in brains of Alzheimer's patients, and are they derived from the proteolytic processing of the beta-amyloid precursor protein (APP). The movement of APP between organelles is highly regulated, and it is tightly connected to its processing by secretases. We proposed previously that transport of APP within the cell is mediated in part through its...

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Identifiers

PMID: 17959829
DOI: 10.1091/mbc.e07-05-0465
PMCID: PMC2174186

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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